| abstract |
Preparation of sulfur-containing benzimidazole derivatives and intermediates. Most of the final products obtained possess useful anthelmintic properties and can be used in human and veterinary therapy as anthelmintic agents. ** (Formula) ** The various symbols have the following definition: R1 is hydrogen or a group of the formula -COOR5, where R5 is C1-4 alkyl; R2 is hydrogen, halogen, C1-6 alkyl trifluoromethyl or a group of the formula -0R3, wherein R3 is C1-4 alkyl, aryl or aralkyl; R4 signifies hydrogen, C1-6 alkyl, C3-7 cycloalkyl, C3-6 alkenyl, C3-6 alkynyl or an aryl or aralkyl group, whereby the aryl ring of the aryl or aralkyl group may be optionally substituted by one or more substituents halogen, C1-4 alkyl, nitro, hydroxy, C1-4 alkoxy, C1-4 alkylthio, carboxy or cyano, or a group of the formula -S (o) n-R8, where R8 is lower alkyl and n means 0 , 1 or 2. |