http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-461193-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e70c0aeade92d7571d955d3b90ea06e |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-84 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-415 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-84 |
filingDate | 1977-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1978-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-461193-A1 |
titleOfInvention | A PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF 4,5DIARIL-2- (SUBSTITUTED TIO) IMIDAZOLE. |
abstract | A process for the preparation of new 4,5-diaryl-2-(substituted thio) imidazole derivatives of formula: **(Formula)** and pharmaceutically acceptable salts thereof, where n is o, 1 or 2; R1 is C1-C4 alkyl; allyl; vinyl; -CH2COCH3; - CH2S(0)m CH3 where m is 0, 1 or 2; mono-and polyhaloC1-C4alkyl; R2 and R3, the same or different, Y1 and Y2, the same or different, represent hydrogen, hydroxy, C1-C4 alkoxy, acetoxy, C1-C4 alkyl, C1, F, CF3, NH2, -N(CH3)2, N02, -NHC-CH3, CH3S-, CH3SO2- or Y1 and Y2 together form a dioxymethylene bridge; with the provisos that when n=0, 1 or 2 and Y1 and Y2 are hydrogen, R1 cannot be vinyl and when R1 is C1-C4 alkyl, C3-C4 haloalkyl with the halogen in positions 3 or 4, allyl or acetonyl, Y1 and Y2 cannot both be H; with the further proviso that when n is 0 and R is CH3, Y1 and Y2 cannot both be p-Cl and p-OCH3. |
priorityDate | 1975-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.