http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-460618-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e77f06144be4708a6ae75bd9fee56a4 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-06086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-6955 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0812 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-087 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-695 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-068 |
| filingDate | 1977-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1979-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-460618-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF PEPTIDE DERIVATIVES |
| abstract | Procedure for the preparation of peptide derivatives of the formula: ALBD-Lis-L-Fen-Gli- (L or D) Lis-L-Pro-L-Val-Gli-L-Lis-L-Lis-X or a derivative functional thereof, where A is an N-terminal chain extension chosen from the group consisting of (1) hydrogen and (2) the N-Acyl radicals derived from (a) alkylcarboxylic acids having from one to about six carbon atoms , (b) aralkylcarboxylic acids having seven to about ten carbons, © amino acids, (d) peptides, (e) the N-alkoxycarbonyl or N-aralkylcarbonyl derivatives of said amino acids, and (f) the N-alcoholylcarabonyl derivatives or N-aralkylcarbonyl of said peptides, B is an amino acid residue chosen from the group consisting of Fen, Trp, Tir and -NH-CHR1-CO-, where R1 is hydrogen or alcohol of one to about six carbon atoms and X is a member selected from the group consisting of hydroxyl, esterified hydroxyl radicals, unsubstituted amino radical, and amino radicals substituted, characterized in that a compound of the formula ALBD-Lis (Q) -L-Fen-Gli (L or D) Lis (Q) -L-Pro-L-Val-Gli-L-Lis (Q) -L-Lis (Q) -X in which (Q) represents an amino protecting group and A, B and X have the meanings defined above, provided that the amino acid residues Lis and Gluen the definition of A and X are provided with a protecting group and the N and / or C terminal amino acid residues are optionally provided with a protecting group is deprotected by means of reduction or hydrolysis at a temperature between -10 ° C and 50 ° C |
| priorityDate | 1976-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.