http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-454640-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05a203d85ee01909eaf728dc16f0f6cb |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-79 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- |
| filingDate | 1976-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1978-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-454640-A1 |
| titleOfInvention | A PROCEDURE TO PREPARE A STABLE ANTIBIOTIC COMPOSITION. |
| abstract | A process for preparing a stable antibiotic composition containing a high concentration of antibiotic in solution, characterized by reacting a tetracycline antibiotic with a suspension comprising a pharmaceutically acceptable alkaline earth metal compound and, if desired, polyvinylpyrrolidone, in 2-pyrrolidone aqueous, to form an alkaline earth metal / tetracycline chelate, and adjust the pH, if necessary, to achieve solution, said antibiotic being selected from among oxytetracycline, doxycycline, tetracycline, chlortetracycline and the pharmaceutically acceptable acid addition salts thereof , with the proviso that when said antibiotic is chlortetracycline, said alkaline earth metal compound is a calcium compound soluble in said solution, and when said antibiotic is different from chlortetracycline, said alkaline earth metal compound is a magnesium compound soluble in said solution. |
| priorityDate | 1976-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.