| abstract |
Compounds of the formula < IMAGE > wherein R1 is hydrogen, -(CH2)n-R4 or -CO-R5, where N IS 1 OR 2, R4 is hydrogen, cyano or benzoyl, and R5 is hydrogen, lower alkoxy, benzyloxy, -CH2-NH2, -CH(CH3)-NH2, -CH2-NH-CH2-C6H5 or -CH(CH3)-NH-CH2-C6H5, R2 is hydrogen or methyl, and R3 is amino, nitro, -NH-CO-R6 or -NH-A-R7, where R6 is hydrogen, methyl, methoxy, ethoxy, methylthio or ethylthio, R7 is amino, methylamino or dimethylamino, and A is -CO- or -SO2-, and non-toxic, pharmacologically acceptable acid addition salts thereof the compounds as well as their salts are useful as hypertensives. |