| abstract |
Alkyne compounds of the formula < IMAGE > wherein R1 is H, alkyl of up to 4 carbon atoms or phenyl R2 is H, aliphatic acyl of up to 6 carbon atoms or aroyl of up to 11 carbon atoms R3 and R4 are H, F, Cl or Br and n is 0 or 1, and physiologicaly acceptable metals salts thereof, have antiinflammatory activity. These compounds can be made from compounds of the formula < IMAGE > wherein Q is a functionally-modified hydroxy and R1, R3, R4 and n are as above by treatment with a solvolyzing agent. |