http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-446538-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9647161fb602828d512f4438d0a865e0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D455-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-233 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-233 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
| filingDate | 1976-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1977-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-446538-A1 |
| titleOfInvention | PROCEDURE TO PREPARE SUBSTITUTE BENZOQUINOLIZNIOS. |
| abstract | Procedure for preparing substituted benzoquinolizines, of formulas: **(See formula)** wherein R1 is hydrogen, methyl or ethyl; R2 is methyl, ethyl, halogen, hydroxy, nitro, amino, acetamido, or formamido; n is 0, 1 or 2 and, when n is 2, R2 can be methylenedioxy or ethylene dioxy attached to adjacent carbon atoms and, when R is ethyl, methoxy, nitro, amino, acetamido or formamido and n is 2, each R2 must to be different; and its lower alkyl esters or pharmaceutically acceptable salts; characterized in that: 1) an alkoxyquinoline of the formula is reacted: **(See formula)** wherein R2 is methyl, ethyl, methoxy, halogen, hydroxy, nitro, amino, acetamido, or formamido; n is 0, 1 or 2 and, when n is 2, R2 can be methylenedioxy or ethylenedioxy attached to adjacent carbon atoms and, when R2 is ethyl, methoxy, nitro, amino, acetamido or formamido and n is 2, each R must be different, and alq is alkyl with 1 to 4 carbon atoms, with methyl- or ethyl-lithium, under dry conditions in an inert solvent, at a temperature of -30 to 0ºC, followed by acid hydrolytic dissociation of the alkoxy group to form a 4-oxo-1,2, -3,4-tetrahydroquinoline intermediate of formula: **(See formula)** where R is methyl or ethyl. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1975-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.