http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-445660-A1

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filingDate 1976-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1977-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-445660-A1
titleOfInvention PROCEDURE TO PREPARE W-ACETYLENE-W-AMINO-ALCA-NOICOS AND 2-ALQUENOICOS ACIDS.
abstract Novel compounds of the following general formula are useful pharmacologic agents: O PARALLEL HC 3BOND C-CH-[A]-C-R2 | NHR R is selected from hydrogen, alkylcarbonyl wherein the alkyl moiety contains from 1 to 4 carbon atoms, alkoxy-carbonyl wherein the alkoxy moiety contains from 1 to 4 carbon atoms and may be straight or branched, and O PARALLEL -C-CH-R10 | NH2 wherein R10 is selected from hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl and p-hydroxybenzyl R2 is selected from hydroxy, a straight or branched alkoxy group of from 1 to 8 carbon atoms, a lower alkylamino group wherein the alkyl moiety contains from 1 to 4 carbon atoms, and -NH-CH-COOH | R4 wherein R4 is selected from hydrogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, benzyl, and p-hydroxybenzyl [A] is selected from R1 | (-CH-)n AND -CH=CH- wherein R1 is selected from hydrogen, lower alkyl of from 1 to 4 carbon atoms, phenyl and substituted phenyl wherein the substituents on the substituted phenyl may be attached at the ortho, meta or para positions of the phenyl ring and are selected from halogen, lower alkoxy of from 1 to 4 carbon atoms, and lower alkyl of from 1 to 4 carbon atoms n is an integer of from 1 to 5 and the lactams of said compounds wherein [A] represents R1 | (-CH-)n R and R1 represent hydrogen and n is the integer 2 or 3 and pharmaceutically acceptable salts and individual optical isomers thereof.
priorityDate 1975-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 37.