http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-445450-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f2d3599fb8f8f479dba95ca9bb504884 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C255-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-90 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-90 |
filingDate | 1976-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1977-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-445450-A1 |
titleOfInvention | A METHOD OF PREPARING 1- (1-PHENYLETHYL) -1H-IMIDAZOL-5- LOWER ALKYL CARBOXYLATE. |
abstract | Optically active C1-C3-alkyl esters of 1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid are prepared by reacting racemic 1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid with an optically active isomer of 1-phenylethylamine, 1-(1-naphthyl)ethylamine or 1-(2-naphthyl)ethylamine. The resulting insoluble diastereomeric salt is separated off and treated with a strong non-oxidising mineral acid. The resulting optically active 1-(1-phenylethyl)-1H-imidazole-5-carboxylic acid is then esterified with a C1-C3-alcohol. In another process, the resulting optically active acid is firstly converted into the acid halide and then correspondingly esterified. The prepared compounds can be used as hypnotics. |
priorityDate | 1975-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.