http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-437081-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f07293d4b34d8372fb0775181fef9d23 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-58 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4468 |
| filingDate | 1975-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1977-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-437081-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF NEW 1- (N- (PARA-FLUO-ROBENZOILPROPIL) -4-PIPERIDIL) -UREAS. |
| abstract | Novel 1-[N-(p-fluorobenzoylpropyl)-4-piperidyl]ureas of the formula I below, in which R is a hydrogen atom, an acetyl group, an alkyl group with 1 to 3 carbon atoms or the phenyl group, are prepared by reacting a correspondingly substituted N-(4-piperidyl)-2-imidazolidinone with a p-fluorobutyrophenone which has in the omega position a group which can be eliminated under the reaction conditions. The products of the process can be converted into their physiologically tolerated acid addition salts. It is additionally possible for resulting compounds of the formula I in which R is hydrogen to be acetylated by reaction with acetyl chloride or acetic anhydride. The novel compounds show the typical range of effects of the neuroleptics and can therefore be employed as CNS-depressant agents, sedatives and tranquillizers. |
| priorityDate | 1974-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.