http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-433990-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d629f98a51b15993f56f9e04fdea237f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-234 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7028 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-236 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 |
| filingDate | 1975-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1977-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-433990-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF DIAMINOCI-CLITOLES. |
| abstract | Procedure for the preparation of diaminocyclitole derivatives, specifically 1-N substituted derivatives of 4,6-di- (aminoglycosyl) -1,3-diaminocyclitols gentamicin A, gentamicin B, gentamicin B1 gentamicin C1, gentamicin Cla, gentamicin C2, Gentamicin C2a, Gentamicin X2, Sisomycin, Verdamicin, Antibiotic G-418, Antibiotic 66-40B, Antibiotic 66-40D, Antibiotic JI-20B, and Antibiotic G-52 where the substituent on 1-N is designated by X, which represents: S-3-amino-2-hydroxypropionyl or S-4-amino-2-hydroxybutyryl with the proviso that, in the case of C1 gentamicin, Cla gentamicin and C2 gentamicin, X is S-3- amino-2-hydroxypropionyl; and its pharmaceutically acceptable acid addition salts; comprising treating one of the aforementioned 4,6-di- (aminoglycosyl) -l, 3-diaminocyclitols which may have amino group protecting groups at any position other than position 1 with an acid of the formula HO - X' wherein X is a group as defined for X above, wherein the amino group and/or the hydroxy group may be protected, in the presence of a carbodiimide, or with a reactive derivative of said above acid, removing all protecting groups present in the molecule and isolating the derivative as such or as a pharmaceutically acceptable acid addition salt. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1974-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.