http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-433677-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a48132fcc2f50a7107021f911f887cb |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J11-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-565 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J11-00 |
filingDate | 1975-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1976-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-433677-A1 |
titleOfInvention | PROCEDURE FOR OBTAINING IN PURE STATE 17 ALPHA-ETHINYL (5ALFA) -2-ANDROSTENE, 17BETA-OL, AND ITS 17BETA ACETATE, FOR APPLICATION IN HUMAN THERAPEUTICS. |
abstract | "PROCEDURE FOR OBTAINING IN THE PURE STATE OF COMPOUND 17α- ETHINYL (5α) -2-ANDROSTENE, 17β-OL, AND ITS ACETATE 17β, FOR APPLICATION IN HUMAN THERAPEUTICS," especially for the treatment of disturbances in ovarian or testicular function, including certain forms of sterility, for the treatment of certain hormo-sensitive tumors of a benign nature (prosthetic adenoma, mammary adenoma or fibro-adunoma) or malignant (breast, ovary, uterus, testis, prostate, etc.), for the treatment of certain states of bone destruction (steoporosis, for example) linked to a primitive or secondary hyperparathyroiditis, for the treatment of hyperfunction of the sebaceous glands (seborrhea, acne), under all the pharmaceutical forms and the appropriate doses to use any of the routes orally, rectally, vaginally and injectable by intramuscular route, and as an oral contraceptive medicine, characterized by the fact that, in a first phase, a mixture of 17-keto (5 alpha) -2-androstene and 17-keto (5 alpha) -3-androstene is subjected to the oxidizing action of the Jones reagent; in a second cap, the oxidized reaction mixture is passed through a chromatography column on silica and the benzene result of the elution is collected in this column, which, in a third stage, is reacted with acetylene in a solution of potassium in t-amyl alcohol, collecting the reaction product by extraction and recrystallization. (Machine-translation by Google Translate, not legally binding) |
priorityDate | 1974-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.