http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-431374-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0d6256baf554e46784d8daa478a2ddc6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
| filingDate | 1974-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-431374-A1 |
| titleOfInvention | A PROCEDURE FOR PREPARING NEW VINYL DERIVATIVES. |
| abstract | A procedure to prepare new vinyl derivatives of general formula (I): **(See formula)** where A is a carbon atom or a nitrogen atom, and R1 is a hydrogen atom or an alcohol group having 1 to 6 carbon atoms, and their salts, which comprises reacting a compound of general formula (a): **(See formula)** where X is a halogen atom, A is as defined above, R2 is a vinyl group or a group (see formula), where Y and Z are different from each other and each represent a hydrogen atom, a halogen atom, a lower alkoxy group, a benzyloxy group, an alcoholic hydroxyl group or a derivative thereof, or a group that can form a tertiary amine, tertiary amine N-oxide, or quaternary ammonium salt or hydroxide by bonding to the residue (see formula) of the group (see formula), with the exception that Y or Z is always a hydrogen atom, and R3 is a hydrogen atom or an alcohol group having 1 to 6 carbon atoms, with a compound of the general formula: **(See formula)** where R1'is a hydrogen atom, an alcohol group having 1 to 6 carbon atoms, or an acyl group, to form a compound of the general formula: **(See formula)** where R1', R2, R3 and A are as defined above, and hydrolyze this compound when R1' is an acyl group or R3 is an alcohol group having 1 to 6 carbon atoms, or subject it to an elimination reaction by heating when R2 is a group of formula (see formula); and because, if desired, compound (I) can be converted into its pharmaceutically acceptable acid or alkali metal addition salts by treatment with acids such as hydrochloric, acetic, lactic, succinic, oxalic, methanesulfonic etc., or chopped alkalis as potassium and sodium hydroxides and carbonates. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1973-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.