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filingDate 1974-10-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1976-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-430656-A1
titleOfInvention PROCEDURE FOR THE PREPARATION OF DISTURBED BENZAMIDES IN POSITIONS 2 AND 5.
abstract Procedure for the preparation of substituted benzamides in positions 2 and 5 of the general formula: **(See formula)** as well as its addition salts, with pharmaceutically acceptable mineral or organic acids and their quaternary ammonium salts: where A in formula (I) is a low molecular weight monoalkoxylamino or dialcoylamino radical in which the alcohol groups can be united together to form a ring with or without nitrogen, oxygen or sulfur, it being the case that when the ring contains a nitrogen atom, the nitrogen atom can be attached to a low molecular weight alcohol group, the rings being thus formed for example: pyrrolidinyl, piperidinyl, imidazolidinyl, piperazine, morpholino, thiazolidinyl, or a heterocyclic radical of the form: **(See formula)** where r is a low molecular weight or alkenyl alcohol radical; where m is an integer less than 4; B can be a low molecular weight alcohol radical or an alkenyl radical; n = 1 or 2, X can be an amino, monoalkoxylamino or dialeohylamino, alcoholic or alkenyl radical, characterized in that said process consists of starting from a benzoic acid disubstituted in positions 2 and 5, of the formula: **(See formula)** where B and X have the same meanings described above and treat it with an amine of formula: H2N (CH2) NA (III) where A has the same value as described above in the presence of trichlorophenylsilane of formula II **(See formula)** such that the desired benzamide of formula (I) is obtained. (Machine-translation by Google Translate, not legally binding)
priorityDate 1973-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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