| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9b86dbdcfe153c2dfb874aff99d07177 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- |
| filingDate |
1974-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1976-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-428386-A1 |
| titleOfInvention |
A PROCEDURE FOR PREPARING 7-ALPHA-AMINOACETAMIDE CEFALOSPORIN-4-CARBOXYL ACID. |
| abstract |
A process for preparing 7-α-amino-acetamido cephalosporin-4-carboxylic acid comprising: (a) the reaction of a 7-amino-cephalosporin-4-carboxylic acid ester with an active form of α-aminoacetic acid, the amino group of which is protected by reaction with a β-dicarbonyl compound to form an enamine; (b) removal of the amino protecting group from the resulting 7-α-aminoacetamido cephalosporin compound; (c) adding to the reaction mixture a quantity of hydrazine or a derivative thereof sufficient to prevent the β-dicarbonyl compound from reacting with the 7-α-aminoacetamido cephalosporin compound obtained in step (b); and (d) if necessary, deesterification of the resulting cephalosporin ester to obtain the desired 7-α-aminoacetamido cephalosporin-4-carboxylic acid. (Machine-translation by Google Translate, not legally binding) |
| priorityDate |
1973-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |