| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_232361c9031a709144573276863c462b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07G-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-32 |
| filingDate |
1974-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
1976-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-427961-A1 |
| titleOfInvention |
A PROCEDURE FOR THE PREPARATION OF A CEPHALEXIN BIS-DIMETHYLFORMAMIDE SOLVATE. |
| abstract |
A process for the preparation of a cephalexin and bis-dimethylformamide solvate, comprising (a) acylating a silylated derivative of 7-ADCA by reaction with phenylglycyl chloride hydrochloride in dimethylformamide, at a temperature not exceeding 0 ° C in the presence of a tertiary nitrogen base having a pka in the range of 3.0 to 7.0 and (b) precipitating the cephalexin product thus formed as a bis-dimethylformamide solvate by diluting the reaction solution with water and adjusting the pH to about 6.9 by adding a base. |
| priorityDate |
1973-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |