http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-427674-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c58fb00bed4fa5b41af6cdf73e6dcf65 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 |
| filingDate | 1974-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-427674-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF DOUBLE SALTS OF S-ADESONIL-1-METHIONINE. |
| abstract | Procedure for the preparation of the double salts of S-adenosyl-L-methicine, (SAM) with sulfuric acid and para-toluenesolphonic acid, characterized in that it comprises the following phases: a) preparing a concentrated solution of SAM; b) precipitate the SAM existing in the solution acidified with a solution of picrolonic acid, c) dissolve the picrolonate of SAM in a mixture consisting of equal parts by volume of an aqueous solution of equal normality of para-toluenesulfonic acid and sulfuric acid and of a organic solvent partially miscible with water, d) precipitating the SAM salt from the aqueous layer with a ketone or alcoholic solvent totally soluble in water. E) dissolving the precipitated salt in a methanolic solution of toluenesulfonic acid and f) precipitating with an organic para-toluenesulfonic solvent and f) precipitating with an appropriate organic solvent the double salt of SAM with sulfuric acid or para-toluenesulfonic acid. |
| priorityDate | 1973-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.