http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-414340-A1

Outgoing Links

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filingDate 1973-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1976-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-414340-A1
titleOfInvention PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF N- (M-TRI- FLUORMETILTIO-FENIL -) - PIPERAZINE.
abstract Procedure for preparing N- (m-trifluoromethylthio-phenyl) -piperazine derivatives of formula (I): ** (See formula) ** where A represents; or a grouping - (CH2) n -COOR, where n is an integer at least equal to 1 and at most equal to 6 and R is a straight-chain or branched alkyl radical containing from 1 to 6 carbon atoms, either a grouping -CH2- (CH2) n-R1 in which n has the same meaning as above and R1 represents either a nitrile function or a carboxylic function, as well as the addition salts that form the amines (I) with any pharmaceutically acceptable mineral or organic acid and, in the case that R1 is a carboxylic function, the non-toxic salts that form the compounds (I) with the mineral bases or with organic bases such as amines; characterized in that N- (m-trifluoromethylthiophenyl) -piperazine of formula (II) is reacted; ** (See formula) ** with an acrylic compound of formula (III); CH2 = CH-T (III) in which T represents either a -CN group, or a -COOR group in which R has the same meaning indicated above. (Machine-translation by Google Translate, not legally binding)
priorityDate 1972-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 25.