http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-413645-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b6435d0d906ff3977f8d4d278106fd5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_579f87aa850cbc61074a160ea38c7d42 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
filingDate | 1973-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1976-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-413645-A1 |
titleOfInvention | PROCEDURE FOR THE PREPARATION OF 1 - DIPHENYL-3,5-DIOXO-4-N-BUTYLPYRAZOLIDINE-2- (BETA-HYDROXYPHENYLETHYLAMINE) -PIRIDI-NA. |
abstract | Process for the preparation of 1-diphenyl-3,5-dioxo-4-N-butylpyrazidine-2- (beta-h.-hydroxyphenylethyl-amino) -pyridine, of the formula ** (see formula) ** Characterized in that, in a water-soluble organic solvent medium, 1-diphenyl-3,5-dioxo-4-N-butylpyrazolidine of the formula is reacted in equimolar proportions. ** (see formula) ** (phenylbutazone) With 2- (beta-hydroxyphenethylamino) -pyridine, of formula ** (see formula) ** (fenyramidol) With formation of the salt corresponding to the bond between the quinic acidic group of the phenylbutazone and the basic group corresponding to the pyridine nitrogen of the feniramidol, whose addition salt formed, of the aforesaid structural formula, is precipitated by its insolubility in a preferably aqueous medium and, once separated from the reaction medium, it is optionally purified by dissolving in a water-soluble organic solvent, preferably methanol, and is reprecipitated by increasing the aqueous proportion of the system. (Machine-translation by Google Translate, not legally binding) |
priorityDate | 1973-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.