http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-412859-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-06 |
| filingDate | 1973-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-412859-A1 |
| titleOfInvention | A PROCEDURE FOR THE PREPARATION OF A DERIVATIVE OF 7- (ALPHA HYDROXY-ALPHA-PHENYL) ACETAMIDO - 3 - (1 - METHYL - 1H - TETRAZOL - 5 - ILTIOMETIL) CEPHALOSPORIN. |
| abstract | A process for the preparation of a 7- (α -hydroxy- α -phenyl) acetamido-3- (1-methyl-1H-tetrazol-5-ylthiomethyl) cephalosporin derivative of the formula: ** (see formula) ** Characterized by: (1) reacting a 7-acyl-amido-3-acetoxymethyl compound of the formula: ** (see formula) ** Where r'is hydrogen, alkyl or 4-amino-4-carboxy-butyl and r is hydrogen or a protecting group of the carboxy radical with 1-methyl-1H-tetrazole-5-thiol or an alkaline, alkaline-earth or ammonium salt thereof to produce a 7-acylamido-3- (1-methyl-1H-tetrazol-5-ylthiomethyl) compound of formula: ** (see formula) ** (2) cleaving the compound 7-acylamido-3- (1-methyl-1H-tetrazol-5-ylthiomethyl) to produce a 7-amino-3- (1-methyl-1H-tetrazol-5-ylthiomethyl) compound of formula ** (see formula) ** And (3) acylating the resulting 7-amino compound with anhydro-0-carboxymandelic acid of formula ** (see formula) ** To produce the aforementioned cephalosporin. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1972-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.