| abstract |
Arylpiperazines of the formula R-A-Z wherein R is OR R2-Q-, in which R1 is H, alkyl, Ar or COR3 R2 is H or alkyl R3 is alkyl, aralkyl or substituted or unsubstituted aryl, and Q is -CX1=CH-CO-, -C 3BOND C-CO-, -CH=CX1-CO-, -CHX1-CHX1-CO-, -CO-CH=CX1-, -CO-C 3BOND C-, -CO-CX1=CH- or -CO-CHX1-CHX1 X1 is a functional group A is CnH2n in which n is 1-4 Z is -NN-Ar AND Ar is unsubstituted or substituted phenyl are produced by reacting a carbonyl compound of the formula R2-Q-Y wherein Y is -A-X1 or -CnH2n-1, with a compound of the formula H-Z to produce novel intermediate products of the formula R2-Q-A-Z which can then be reacted with a hydrazine derivative of the formula R1-NH-NH2 to produce a pyrazolylalkyl piperazine as defined above. |