http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-410249-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2375-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2483-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J9-0061 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G18-4072 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G77-46 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D257-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D271-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G77-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-00 |
filingDate | 1972-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1976-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-410249-A1 |
titleOfInvention | A PROCEDURE FOR THE PREPARATION OF HALOPHENYLTHIOACETAMIDOCEPHALOSPORANIC DERIVATIVES. |
abstract | A process for the preparation of halofenylthioacetamidocephalosporin derivatives of the formula: ** (see formula) ** Where z is hydrogen or fluorine, and when z is hydrogen x and y are hydrogen or chlorine, selected so that the phenyl ring is substituted with one or two chlorine atoms and so that when a single chlorine atom is present, it is in position 3 and when two chlorine atoms are present, they are in positions 3,4, 3,5 or 2,5; and when z is fluorine it is in the 3 or 4 position of the phenyl ring, and each of x and y is hydrogen or chlorine, so that when the phenyl ring is substituted with one or two chlorine atoms, one of which is in the 3 or 4 positions of the phenyl ring; R is hydrogen, 5-methyl-1,3,4-tiadiazolyl-2-tio, 1-methyl-5-tetrazolylthio, 1H-tetrazol-5-ylt, 5-phenyl-1,3,4-oxyadiazolyl-2- that, 5- (p-nitrofenyl) -1,3,4-oxadiazolyl-2-tio, 5- (p-methoxyphenyl) -1,3,4-oxadiazolyl-2-thio, carbamethoxy, methylcarbamoyloxy, thiomethyl, pyridine, azide or dithycarbamoyl and R'is hydrogen, dicyclohexylamine or a pharmaceutically acceptable cation; Whose procedure is characterized by: A) N-acylate a compound of formula ** (see formula) ** Where r and r'have the meaning defined above, with an acylating agent comprising an acid of formula ** (see formula) ** Or the corresponding acyl halide, anhydride or mixed anhydride, wherein x, y and z have the meaning given above; and optionally preparing the salts thereof. (Machine-translation by Google Translate, not legally binding) |
priorityDate | 1971-12-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.