http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-408156-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bba842fc4d37dfcaced1b55bc0c91c7c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-68 |
| filingDate | 1972-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1976-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-408156-A1 |
| titleOfInvention | PROCEDURE FOR OBTAINING QUINAZOLINONES. |
| abstract | Procedure for obtaining quinazolinones, of formula I, **(See formula)** where it means an alkyl radical of 1 to 5 carbon atoms that is not a tertiary alkyl radical where the tertiary carbon atom is linked directly to the nitrogen atom of the ring, an allyl, metalyl or propargyl radical, each of R2 and R3, which may be the same or different, means a hydrogen, fluorine, chlorine or bromine atom, an alkyl, alkylthio or alkoxy radical of 1 to 3 carbon atoms or a nitro or trifluoromethyl group, with the proviso that only one of R2 and R3 means an alkylthio radical or a nitro or trifluoromethyl group, and R4 means a radical of formula II, **(See formula)** wherein each of Y1 and Y2, which may be the same or different, means a hydrogen, fluorine, chlorine or bromine atom, an alkyl or alkoxy group of 1 to 3 carbon atoms or a trifluoromethyl group, with the proviso that only one of Y1 and Y2 signifies a trifluoromethyl group, provided that when R1 signifies an isopropyl radical, R2 signifies a 7-methyl radical, and R3 signifies a hydrogen atom, then R4 has a meaning other than a p- radical. fluorophenyl, characterized in that a compound of formula III is cyclized, **(See formula)** wherein R1, R2, R3 and R4 have the meanings indicated above, at a temperature of at least 80ºC, conveniently between 80 and 160ºC, preferably between 100 and 130ºC, in the presence of carboxylic acid of 2 to 4 carbon atoms, conveniently acetic or propionic acid, preferably glacial acetic acid, using a molar ratio of urea to compound III of at least 3, suitably between 3: 1 and 20: 1, conveniently between 4: 1 and 15: 1, preferably between 5: 1 and 10: 1. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1971-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.