http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-405649-A1

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filingDate 1972-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1975-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-405649-A1
titleOfInvention PROCEDURE FOR THE PREPARATION OF NEW ACIDS 4 - (4-BIPHENYLIL) - 4 - HYDROXY - BUTYRICS, THEIR ESTERS OR LACTUS.
abstract Procedure for the preparation of new 4- (4-biphenyl) -4-hydroxy-butyric acids, their esters or lactones of the general formulas I and II **(See formula)** wherein R1 signifies a hydrogen or halogen atom, the cyano, nitro group, or an amino group optionally substituted by an acyl radical with 1 to 4 carbon atoms; R2 means a hydrogen atom, a halogen atom or an alcohol radical with 1 to 3 carbon atoms; R3 signifies a hydrogen or halogen atom; and R4 means a hydrogen atom or an alcohol group with 1 to 4 carbon atoms and, if R4 represents a hydrogen atom, its salts are physiologically compatible with organic or inorganic acids, characterized in that a 5- (4-biphenyl) -2 (3H) -furanone of the general formula III **(See formula)** wherein R1 to R3 have the meanings indicated above and the compound obtained from formula II is cleaved, if desired, by hydrolysis to form a compound of general formula I; and/or a compound of the general formula I, in which it represents a hydrogen atom, is transformed, if desired, into a physiologically compatible salt by means of an organic or inorganic base, and/or by means of usual methods in its esters of the general formula I, preferably passing through its acid halide. (Machine-translation by Google Translate, not legally binding)
priorityDate 1971-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 31.