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filingDate 1972-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1975-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-401332-A1
titleOfInvention PROCEDURE FOR THE PREPARATION OF SULFAMIDES.
abstract Procedure for the preparation of sulfa drugs of the general formula ** (See formula) ** wherein R1 signifies a hydrogen atom, a lower alcohol radical or, together with R2, a tetramethylene or pentamethylene radical; R2 signifies a lower alcohol radical or, together with R1, a tetramethylene or pentamethylene radical; R3 signifies hydrogen or the hydroxy group; R4 represents hydrogen, the methyl or ethyl group; R5 signifies hydrogen, a straight-chain or branched-chain alcohol radical, which may also be substituted by a heterocyclic radical, or an aralkoxy or aryloxyalkyl radical, in which the aryl group may also be substituted, in the form of racemates, optionally in pairs of diastereoisomeric antipodes, and of the optical antipodes as well as the corresponding acid addition salts, characterized in that from a compound of the formula ** (See formula) ** in which R6 designates a protecting group capable of being removed by hydrolysis or by hydrogenolysis, and R7 designates a protecting group capable of being removed by hydrolysis, by hydrogenolysis, by transesterification or by ether cleavage agents, and in each case one of the radicals R6 and R7 can also represent hydrogen, the protecting group or protecting groups are removed simultaneously or optionally successively; and because, if desired, the products obtained are split into the optical antipodes or optionally into the pairs of diastereoisomeric antipodes, bases obtained primarily are transformed into salts by addition of acid and salts by addition of acid obtained primarily are transformed into free bases or salts of other acids. (Machine-translation by Google Translate, not legally binding)
priorityDate 1971-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 35.