abstract |
Procedure for obtaining inhibitors for glycoside hydrolases, characterized in that it comprises cultivating a strain of actinomyces, especially actinoplanaceans and streptomycetaceae, in a culture medium; incubate the culture for 1 to 10 days, at a temperature of 15 to 60ºC, preferably 24-50ºC; separate the mycelium from the culture solution and, depending on the presentation of the inhibitors, the effective principle of the culture solution and/or the mycelium is enriched and separate the inhibitors from the culture broths by lyophilization or by precipitation with salts or solvents organic soluble in water or by adsorption of active substances on ion exchange agents. (Machine-translation by Google Translate, not legally binding) |