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filingDate 1971-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1974-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-394917-A1
titleOfInvention PROCEDURE FOR THE PREPARATION OF NEW 1-FENOXI-2-HI-DROXI - 3 - ALCOHYLAMINOPROPANOS RACEMICOS OR OPTICALLY AC-TIVE.
abstract Procedure for the preparation of new racemic or optically active 1-phenoxy-2-hydroxy-3-alcoholylaminopropanes of the general formula **(See formula)** where R means an alcohol group with 1 to 5 carbon atoms; R1 signifies a nitrile (-C = N), carboxy, hydroxy, amino, nitro or trifluoromethyl group or an alcoholic, alkenyl, alkynyl, alkoxy, alkenyloxy, alkynyloxy, hydroxyalkyl, alkoxyalkoxy, dialkoxylaminoalkyl, dialkoxylaminoalkyl group nitriloalkoxy, alkoxycarbonyl, alkylaminocarbonyl, alcoholylthio, acyl, acyloxy or acylamino with up to 5 carbon atoms, an aryl, aralkoxy, aryloxy, aralkoxy or arylamino group with up to 10 carbon atoms or a halogen atom; stands for hydrogen, a halogen atom, a nitrile group or an alcohol, alkoxy or alkenyl group with up to 5 carbon atoms or together with R1 a 3,4-methylenedioxy group (without other substituents); R3 signifies hydrogen, a halogen atom, an alcohol or alkoxy group with up to 5 carbon atoms; and n signifies an integer from 2 to 7, as well as its physiologically compatible acid addition salts, characterized in that a urea derivative of the general formula is hydrolyzed or pyrolyzed **(See formula)** where R, R1 to R3 and n have the meanings mentioned above and R4 as well as R5 (which may be the same or different) signify hydrogen or an alcoholic radical (preferably lower alcoholic), an aralcohyl radical (preferably the benzyl radical) or a aryl radical (preferably the phenyl radical), and because eventually the racemic compounds obtained from formula I are transformed, by reaction with appropriate auxiliary acids, into their diastereoisomeric salts, and the latter are separated by fractional crystallization. (Machine-translation by Google Translate, not legally binding)
priorityDate 1969-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 47.