http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-394771-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da54f7ebbd2d9d8a82f92aca4d1b4e48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 |
| filingDate | 1971-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-394771-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF 17 ALPHA - HYDROXY -16 ALPHA, 18 - DIMETHYL-4-PREGNEN-3,20-DIONA AND ITS 17 ALPHA-MONO-ESTERS OR 9-ENOL - 17 ALPHA - DIESTERS. |
| abstract | Procedure for the preparation of 17α-hydroxy16α, 18-dimethyl-4-pregnen-3,20-dione and their 17α-monoesters or 3-enol-17α-diesters of the general formula I ** (See formula) ** in which R means a hydrogen atom or an acyl radical, characterized in that in a manner known per se: a) a corresponding 17α-hydroperoxy-3-keto- Δ 4-steroid is reduced, optionally after intermediate protection, by for example by catalyzing the 3-keto group, and if desired thereafter the obtained 17α-hydroxy group is esterified and optionally a resulting enol ester group is partially saponified in position 3; or b) a corresponding 3-hydroxy-17α-acyloxy- Δ 5-steroid is oxidized, and if desired the 17α-acyloxy group is then hydrolyzed or the 3-keto- Δ 4 group is transformed into the enolester form, or a 17a-acyloxy group saponified primarily with the desired acid is ultimately esterified, and if desired a 3-enol ester pool is saponified which eventually has resulted at the same time; or c) a corresponding 3,17-dihydroxy- Δ 5-steroid is oxidized, and if desired the 3-keto-17-hydroxy-steroid obtained is subsequently esterified and optionally partially saponified a resulting enol ester group in position 3. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1970-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID458392451 |
Total number of triples: 14.