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filingDate 1971-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1974-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-392074-A1
titleOfInvention A PROCEDURE FOR PREPARING PROSTAGLANDIN CLATRATE COMPOUNDS.
abstract A method of producing clathrate compounds of prostaglandins or their analogs with cyclodextrin, comprising reacting a prostaglandin or its analog of the formula **(See formula)** in which (see formula) is **(See formula)** each of the B and X is -CH2CH2 or -CH = CC-, C is a saturated or unsaturated alcohol group with 3-4- carbon atoms, D is -CH2OH or -COOR1, where R1 is hydrogen or a group alcohol with 1-10 carbon atoms and with or without a substituent containing one oxygen atom, Y is hydrogen or a methyl group and Z is an alcohol group saturated or not with 5-9 carbon atoms or -EF where E is an alcoholic group with 1-4 carbon atoms and F is a phenyl, cyclohexyl or cyclopentyl group; with beta-cyclodextrin or a mixture of alpha-, beta- and gamma-cyclodextrins of the formula **(See formula)** where n is 4,5,6, or mixtures thereof, at a temperature of 70ยบ or less with the molar ratio of prostaglandin or its analog to cyclodextrin being 1: 4-12. (Machine-translation by Google Translate, not legally binding)
priorityDate 1970-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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