http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-389343-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-71 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N47-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N47-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-90 |
| filingDate | 1971-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1975-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-389343-A1 |
| titleOfInvention | A PROCEDURE FOR PREPARING 1-SUBSTITUTE -2 - (1,1-DIFLUOROALCOHYL) -1H-IMIDAZO (4,5-B) PYRIDINE COMPOUNDS. |
| abstract | A process for preparing 1-substituted 2- (1,1-difluoroalcohyl) -1H-imidazo (4-, 5-b) pyridine compounds, characterized by formula I **(See formula)** wherein R1 represents hydrogen, chlorine, fluorine, C1-C6 perfluoroalkyl, or a radical of the formula: **(See formula)** where each Z independently represents hydrogen or halogen and n represents 0 or 1; R2 represents halogen, nitro, -CF3, -CF2C1, -CF2H, or C1-C4 lower alcohol-sulfonyl; and R3 represents hydrogen, alkali metal or alkaline earth metal, or organic amine having a Kb of the order of 10-5 or greater; which comprises reacting a 5-substituted 2-amino-3-nitropyridine, of the formula **(See formula)** wherein R2 is as defined above, with the difluoroalkanoyl halide of formula **(See formula)** or with the difluoroanhydride of the formula **(See formula)** where X is halo and R1 is as defined above, to form the 5-substituted 3-nitro-2- (1,1-difluoroalkoxylamido) pyridine of formula **(See formula)** wherein R1 and R2 are as defined above, and reducing 5-substituted 3-nitro-2- (1,1-difluoroalkoxylamido) pyridine to obtain the 6-substituted 1-hydroxy-2- (1, compound 1-difluoroalcohyl) -1H-imidazo (4,5-b) pyridine desired; and if desired, convert the 6-substituted 1-hydroxy-2- (1,1-difluoroalcohyl) -1H-imidazo (4,5-b) pyridine from step 1, into the alkali, alkaline-earth metal salt or amine, where the amine is an organic amine having a Kb of the order of 10-5 or greater. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1970-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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