http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-387059-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0ff16e899ce32685c9600075c1cc21 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C275-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C239-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
| filingDate | 1971-01-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1974-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-387059-A1 |
| titleOfInvention | PROCEDURE FOR OBTAINING NEW 1- (UREIDOPHENOXY) -2-HYDROXY-O-AMINOPROPANES. |
| abstract | Procedure for obtaining new 1- (ureidophenoxy) -2-hydroxy -3-amino-propanes, of formula **(See formula)** wherein R1 signifies hydrogen or a monovalent hydrocarbon residue, containing 1 to 7 aliphatic carbon atoms, of which one is attached to the nitrogen atom, and R2 signifies a monovalent hydrocarbon residue, containing 1 to 7 carbon atoms aliphatic, of which one is attached to the nitrogen atom, or R1 and R2 together represent a bivalent aliphatic hydrocarbon residue with 4 to 6 carbon atoms or a bivalent aliphatic hydrocarbon residue, interrupted by an oxygen, sulfur or nitrogen atom, with 4 or 5 carbon atoms, R3 means an aliphatic or cycloaliphatic moiety containing 1 to 7 carbon atoms with 3 to 7 ring members and R4 means hydrogen, lower alkyl with 1 to 4 carbon atoms, lower alkenyl with 2 to 4 carbon atoms, lower alkynyl with 3 carbon atoms, cycloalkyl with 3 to 7 ring members, lower phenylalkyl with 1 to 4 chain carbon atoms, lower alkoxy with 1 to 4 atom os of carbon, phenyl, lower alkenyloxy with 2 to 4 carbon atoms, lower alkynyloxy with 3 carbon atoms, halogen, phenoxy, trifluomethyl or cyano, the ureido moiety being in the meta or para position relative to the moiety bearing R3, and its salts, characterized in that a compound of the general formula is reacted **(See formula)** with a compound of general formula Z2 - R3 or the salts thereof, in the presence of a basic condensing agent, where R1, R2, R3 and R4 have the meanings indicated for formula I, one of the residues Z1 and Z2 means an esterified hydroxyl group, capable of reaction and the another signifies the amino group, and X1 signifies a hydroxyl group or, when Z2 is an amino group, Z1 together with X1 forms an epoxy group, the ureido moiety being, in each case, in the meta or para position relative to the moiety that bears R3 and, if desired, the obtained isomer mixtures are separated into the pure isomers and/or the racemates obtained are separated into the optical antipodes and/or the free bases obtained are transformed into their salts or the salts obtained from the bases free. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1970-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.