http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-363815-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D261-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D275-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D291-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- |
| filingDate | 1969-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1970-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-363815-A1 |
| titleOfInvention | PROCEDURE FOR OBTAINING SULFONYLUREAS. |
| abstract | Process for obtaining sulfonylureas containing heterocyclic acylamino radicals, characterized in that amines of general formula hnr'''r'''', in which r''' and r "'''mean hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl radical phenoxyalkyl, cycloalkyl, cycloalkylalkyl, bicycloalkyl, bicycloalkylalkyl, tricycloalkyl, tricycloalkylalkyl, tetracycloalkyl, tetracycloalkylalkyl, optionally substituted alkyl, aryl or aralkyl radicals, optionally substituted by halogen, alkyl, alkoxy or trifluoromethyl radicals, or else, together with the nitrogen atom bonded thereto, a monocyclic or polycyclic radical, containing one or more heteroatoms, optionally substituted by alkyl radicals, optionally also in the form of their salts, are reacted with arylsulfonamide derivatives, which contain acylamino radicals heterocyclic, of general formula ** (see formula) ** Wherein r, means hydrogen or an alkyl radical, r'and r "signify hydrogen, halogen atoms, alkyl radicals or aryl, aralkyl or cycloalkyl radicals, optionally substituted by halogen, alkyl, alkoxy or trifluoromethyl radicals, and further x means an oxygen atom, a sulfur atom, a nitrogen atom substituted by hydrogen, an alkyl radical, an aryl or aralkyl radical, optionally substituted by halogen, alkyl, alkoxy or trifluoromethyl radicals, y means a direct bond, a straight or branched alkylene radical having 1 to 8 carbon atoms and n represents a number from 0 to 4, the substituents on the benzene ring are in the ortho or meta position, preferably, however, in the para position and a is a radical which, during the course of the reaction, is removed with the nitrogen atom, which is found in the nitrogen of the amine nhr'''r'''', by cleavage of an ha compound, or with arylsulfonyl isocyanate corresponding cough ** (see formula) ** Here, a, for example halogen, means an azido, alkoxy, aryloxy, alkylmercapto, arylmercapto, amino, cyclic amino or acylamino radical, optionally substituted. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1967-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.