http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-360999-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_366a19489c5e7eec53d9d57c5ca5657b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-088 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-088 |
| filingDate | 1968-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1970-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-360999-A1 |
| titleOfInvention | PROCEDURE FOR THE OBTAINING OF NEW DIAZOCICLOALKANOSN, N'-DISUSTITUIDOS, RENTED IN THE CARBON OF THE HETEROCICLO, AND OF ITS ACID SALTS OF ADDITION PHARMACOLOGICALLY I- NOFENSIVE. |
| abstract | Process for obtaining new N, N'-disubstituted diazacycloalkanes, alkylated at the carbon of the heterocycle, and their pharmacologically harmless acid addition salts of the general formula II **(See formula)** - where R1, R2, R3 and R4, which may be the same or different, are hydrogen atoms or low molecular weight alkyl radicals with 1-4-carbon atoms, and at least one of the groups R, R, R and R is one such alkyl residue, and m represents 0 or the number 1 and n represents 2 or 3 - as well as its pharmacologically harmless acid addition salts, characterized by the fact of reacting: A) a 3,4,5-trimethoxy-benzoic acid halogenoalkyl ether of the general formula IV **(See formula)** - where n has the same meaning as in formula II and Hal is a halogen atom, and preferably chlorine or bromine - with a diazaocycloalkane of the general formula V **(See formula)** - where R1, R2, R3, R4 and m have the same meaning as in formula II, or B) a 3,4,5-trimethoxy-benzoic acid halide, especially bromide or chloride, an ester, especially a lower alkyl ester of this acid or the anhydride of this acid with an N, N'-bis- (Hydroxyalkyl) -diazaocycloalkane of the general formula VI **(See formula)** - where R1, R2, R3, R4, m and n have the same meaning as in formula II - or C) a salt, especially a salt of an alkali metal or an alkaline earth metal of 3,4,5-trimethoxybenzoic acid, with an N, N'-bis- (Haloalkyl) -diazacycloalkane of the general formula VII **(See formula)** - where R1 R2, R3, R4, m and n have the same meaning as in formula II and Hal is a halogen atom, preferably a chlorine or bromine atom, and especially a chlorine atom. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1967-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.