http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-353768-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b6fc801b5bfe5304ffa40d938db6e09 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-08 |
| filingDate | 1968-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1969-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-353768-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF NEW 1-SUBSTITUTED 3-ARILSULFONI- LUREAS. |
| abstract | Novel compounds I (including salts with bases) wherein R signifies H, F, Cl, Br, NH 2 , alkyl, alkoxy, alkylthio, or alkanoyl, are obtained by reacting an appropriate sulphonyl-isocyanate or -isothiocyanate, or a reactive functional derivative of an appropriate sulphonyl-carbamic acid or -thiocarbamic acid (each foregoing reactant being substituted by the group R or by a group which can be converted into the amino group by hydrolysis or reduction) with 1-amino-2-oxaadamantane (obtained by the hydrogenation of 1 - benzylamino - 2 - oxa - adamantane hydrochloride which, in turn, is obtained by treating 3 - benzylamino - 2 - oxa - adamantan - 1 - ol with lithium aluminium hydride this aminoalcohol is prepared by the interaction of bicyclo- [3,3,1]-nonan-3,7-dione and benzylamine 1- amino-2-oxa-adamantane hydrochloride is also described) or with an alkali metal derivative thereof where necessary resulting thioureas are converted into the corresponding ureas. 1 - (p - Tolylsulphonyl) - 3 - (2 - oxa - adamant- 1-yl)-thiourea is prepared by the interaction of p-tolylsulphonyl isothiocyanate and 1-amino-2- oxa-adamantane. Pharmaceutical preparations having hypoglycemic action contain as active ingredient compounds I administration is orally or parenterally. |
| priorityDate | 1967-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.