http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-350986-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e4ca725f8773226f8e0d07f6b7c17ed |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C309-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C309-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-15 |
| filingDate | 1968-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1969-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-350986-A1 |
| titleOfInvention | A PROCEDURE FOR THE PREPARATION OF 2-ALCOXI-5-N ACIDS (SUBSTITUTED OR NOT) - BENZOIC SULFAMIDE. |
| abstract | The invention comprises compounds of the Formula I: in which A is an alkyl C 1 _ 5 or alkenyl radical C 1-5 and B is an amino or mono- or dialkylamino radical of low molecular weight C 1-5 in which the alkyl groups may be joined together by a -CH 2 - group or a N, O or S atom, to form a heterocycle having up to 5 carbon atoms, and the N atom may be linked to an alkyl group of low molecular weight C 1-5 , which may be prepared by treating a 2-alkoxy-5-chlorosulphonylnitrobenzene with ammonia or an amine, reducing the 2-alkoxy-5-N-(substituted or unsubstituted)-sulphamido-nitrobenzene formed, diazotizing the amino derivative formed and converting the diazo compound into a nitrile by the Sandmeyer method to obtain the nitrile I. This may subsequently be hydrolysed, if desired, to the acid. The preparations of 2- methoxy-5-sulphamido-benzonitrile, 2-ethoxy- 5 - dimethylsulphamido - benzonitrile and the corresponding benzoic acids are described. Heterocyclic ring systems defined by B include pyrrolidine, piperidine, imidazolidine, piperazine, morpholine or thiazolidine. p-Chlorosulphonyl-ethoxybenzene is prepared by treating ethoxybenzene with sulphuric chlorohydrin. 2 - Ethoxy - 5 - chlorosulphonyl-nitrobenzene is prepared by nitrating p-chlorosulphonyl-ethoxybenzene. 2 - Methoxy - 5 - chlorosulphonyl - nitrobenzene is prepared by treating the sodium or ammonium salt of 3-nitro-4-methoxy-benzene sulphonic acid with phosphorus pentachloride. Ammonium 3 - nitro - 4 - methoxybenzene sulphonite is prepared by reacting ammonia with 2 - methoxy - 5 - chlorosulphonyl - nitrobenzene which is prepared by reacting sulphuric chlorohydrin with 2-nitro anisole which is prepared by reacting o-nitrophenol with dimethyl sulphate. Sodium 3 - nitro - 4 - methoxybenzene sulphonate is prepared by reacting phenol with sulphuric acid and sodium nitrate. |
| priorityDate | 1967-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.