http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-346131-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_359b45ab51dbd97bd513b984a50c5ef0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-673 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B61D7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-63 |
| filingDate | 1967-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1969-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-346131-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF EFFECTIVE COMPOUNDS IN THE TREATMENT OF BRONCHOSPATIC CONDITIONS. |
| abstract | Compounds of the general formula (R = tert.-butyl, cyclobutyl, cyclopentyl R5 = OH, C 1-5 alkanoyloxy) and their salts are prepared by (a) reducing a compound of the formula (R3 = H or group replaceable by H) in the presence of RNH 2 , followed by replacement of R3 if necessary (b) reacting a compound of the formula with RR4NH (R4=H, aralkyl), followed by replacement of R3'4, if necessary (c) reducing a compound of the formula followed by replacement of R3'4 if necessary or (d) hydrogenating a compound of the formula reacting the product with cyclobutanone or cyclopentanone, further hydrogenating the reaction mixture and replacing R3 if necessary optionally followed in each case by salt formation. The preparation of starting materials for processes (a), (b), (c) and (d) by standard methods and of ethyl 3,5-dihydroxybenzoate, 3,5- dibenzyloxybenzoic acid, 3,5-dibenzyloxybenzoyl chloride, 3,5 - dibenzyloxy - # - bromoacetophenone, 3,5 - dibenzyloxy - # - chloroacetophenone and 3,5-dibenzyloxyacetophenone is described. The compounds of the invention are bronchodilators, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier. |
| priorityDate | 1966-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.