http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-344357-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N53-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N53-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N53-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-80 |
| filingDate | 1967-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1969-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-344357-A1 |
| titleOfInvention | A PROCEDURE TO PREPARE CYCLOPROPANOCARBOXYLATES. |
| abstract | Novel substituted phthalans of the formula <FORM:1117625/C2/1> where R is a di-C1- 6 alkylamino-C1- 6 alkyl radical, an amino-C1- 6 alkyl radical, a mono-C1- 6 alkylamino-C1- 6 alkyl radical or a group comprising a heterocyclic ring linked via a N atom to a C1- 6 alkyl attached to the phthalan nucleus, and each R1 represents H or each R1 represents an alkyl, aryl, aralkyl or heterocyclic radical, are obtained (a) by treating a substituted phthalan of the formula <FORM:1117625/C2/2> in which R1 is H, with a mineral acid to form the acid addition salt and subsequently heating the salt in the presence of p-toluene sulphonic acid as a melt to form the desired phthalan in which each R1 is H or (b) by treating the corresponding phthalan II in which each R1 is an alkyl, aryl, aralkyl or heterocyclic radical with a mineral acid to form the desired substituted phthalan. Pharmaceutical compositions, having anti-inflammatory, diuretic and analgesic activity, comprise compounds of Formula (I), either as free bases or in the form of non-toxic pharmaceutically acceptable acid addition salts or quaternary ammonium salts, together with pharmaceutical diluents or carriers in dosage forms such as tablets, suspensions, solutions or suppositories. |
| priorityDate | 1966-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.