http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-338535-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bf2ba08adb8ed810fa2aafc13dea308 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D319-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D265-32 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D319-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-32 |
| filingDate | 1967-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1968-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-338535-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF L - (-) - ALPHA-METHYL - BETA- - (3,4-DIHYDROXYPHENIL) -ALAMINE. |
| abstract | L - (-) - a - methyl - b - (3,4 - dihydroxy-phenyl)-alanine is prepared by reacting 3,4-dimethoxy - phenyl - acetone with an alkali metal cyanide and L - (+) - threo - 2,2 - dimethyl - 4 - phenyl - 1,3 - dioxan to give an optically active amino nitrile of the formula <FORM:1114017/C2/1> mixing said amino-nitrile with concentrated hydrochloric acid at a reduced temperature and subsequently warming up the reaction mixture, saponification taking place to give a lactone hydrochloride of the presumed formula <FORM:1114017/C2/2> which is then reacted with either hydrogen peroxide or Raney nickel and the resulting L-(-)-a - methyl - b - (3,4 - dimethoxyphenyl) - alanine is finally demethylated with hydrobromic acid. |
| priorityDate | 1966-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.