http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-336254-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e5edd48190cba3fa70dd3975efd9831 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-108 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-108 |
| filingDate | 1967-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1968-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-336254-A2 |
| titleOfInvention | PROCEDURE FOR OBTAINING THERAPEUTICALLY ACTIVE ALPHA - PYRROLIDINOCETO- NAS. |
| abstract | Improvements in the object of the main Patent No. 266,271 by: Process for the preparation of therapeutically active alpha-pyrrolidinocetones, of the general formula ** (See formula) ** wherein R represents a hydrogen atom, a lower alkyl radical, a lower alkoxy group, a hydroxyl group or a halogen atom, R 'an alkyl radical having 2 to 8 carbon atoms, and R "a hydrogen atom or an alcohol radical, characterized in that an α-pyrrolidinonitrile of the formula ** (See formula) ** wherein R 'and R "have the above meanings, is reacted with a phenyl-lithium of the formula ** (See formula) ** wherein R '' 'has the meanings of R, with the exception of a free hydroxyl group, the reaction being carried out in an anhydrous organic solvent, preferably at temperatures between -10 and + 40º C. and conveniently employing a slight excess of the phenyl-lithium compound, and in the case of producing a product in which R represents an alkoxy group, it is transformed, if desired, subsequently into a free hydroxyl group, in the manner in which yes known. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1966-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 15.