http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-315441-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_484ac5ba7137961493a6b9598c4b7d6a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-1745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C43-1742 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-174 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-12 |
| filingDate | 1965-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1966-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-315441-A1 |
| titleOfInvention | PROCEDURE FOR THE MANUFACTURE OF AMINES FOR PHARMACEUTICAL USES |
| abstract | Compounds of the general formula <FORM:1119835/C2/1> wherein A represents an alkyl, aryl, substituted aryl, aralkyl or substituted aralkyl group, a benzyloxymethyl group (in which the benzene ring may optionally be substituted by one or two halogen atoms, a trifluormethyl group or one or two methyl groups) or a benzhydryloxymethyl group (in which one of the benzene rings may optionally be substituted by one or two halogen atoms, a trifluoromethyl group or one or two methyl groups), R represents an alkyl, aralkyl or substituted aralkyl group or an alkyl group bearing a heterocyclic group and B represents an alkylamino, cycloalkylamino, alkenylamino, hydroxyalkylamino, aralkylamino, 1-pyrrolidinyl, piperidino or morpholino group, a 1-piperazinyl group (which may optionally be subtituted in the 4-position by an alkyl, aryl, aralkyl, diaralkyl, ar-haloaralkyl, haloalkyl, hydroxyalkyl, acyloxyalkyl, diaralkyloxyalkyl or ar-trimethoxybenzyl group) or a group of the formula-NR2R3 in which R2 and R3 are the same or different and each represents an alkyl, hydroxyalkyl, acyloxyalkyl or aralkyl group, and their acid addition and (in the case of tertiary amino compounds) quaternary ammonium salts are prepared by reacting ACH = CH2 with ROH in the presence of t-butyl hypobromite in the cold and heating the resulting ACH(OR)CH2Br with BH, optionally followed by salt formation. |
| priorityDate | 1964-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.