http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-300797-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1cba2cfcc99735c4b0de18a5ac3dd3a9 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K- |
| filingDate | 1964-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1964-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-300797-A3 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF THEBAINE AND ORIPAVIN COMPOUNDS |
| abstract | Process for the preparation of thebaine and oripavine compounds in which R is a methyl group and in which R3 does not contain the -CH-aryl or -CH-CC system directly linked to the carbon atom bearing the alcoholic hydroxyl group, characterized wherein a compound of formula: ** (See formula) ** is treated with cyanogen bromide, in which the resulting N-cyano-compound is hydrolyzed by heating in a solvent with an alkali metal hydroxide or alcoholate at temperatures up to 180ยบ C, in which the resulting secondary amine is converted to a tertiary amine, either by treatment with an alkyl halide, alkenyl halide or cycloalkyl halide, or by treatment with an acyl halide, followed by a reduction with lithium aluminum hydride. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1964-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.