| abstract |
Among other aspects, the present invention provides methods for the manufacture of blood protein compositions from pooled plasma. In one embodiment, the invention provides an alcohol fractionation scheme that allows for significant increases in the yield of blood proteins purified from the initial plasma sample. In a specific embodiment, a method for fractionating pooled plasma is provided, the method comprising an initial high alcohol, low pH precipitation step. The present invention also provides therapeutic blood protein pharmaceutical compositions. (Automatic translation with Google Translate, without legal value) |