| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73e0d5808f34f512649e277bd216a344 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate |
2015-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2a13630b16c1233dc6b41416a6fa0cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e095c14fdf1de2b02052be8620f2edab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0b884943016c7754cd10c178fe4d1ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b9fd6f58d38097f980ffbb44d977fda
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adb8ddc3a1bd0d347868ec3514952d1d |
| publicationDate |
2022-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2926641-T3 |
| titleOfInvention |
N2-phenyl-pyrido[3,4-d]pyrimidine-2,8-diamine derivatives and their use as MPS1 inhibitors |
| abstract |
The present invention relates to compounds of formula I wherein R1, R2, R3 and R4 are all as defined herein. Compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 kinases (Mps1 - also known as TTK), either directly or indirectly through interaction with Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention is also related to the processes for the preparation of these compounds, and to the pharmaceutical compositions that contain them. (Automatic translation with Google Translate, without legal value) |
| priorityDate |
2014-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |