| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a0ee415d0eb25013522821450509da91 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-385
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1077
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-20 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-34 |
| filingDate |
2018-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_160049a6c56b6dea80efa0f3cc2df1a1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a21238e62da64bf56853b1e26a19029
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0824d6e91ddb6b0e2fa8ec766b1c5363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c568747e6e840a9540d6d60a2e451413
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e95db33f48644c2c4ffecf772cee7f8a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5b9614626aeff8767553a8da9ebb805
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5600cb142bc8b26307a3d029713333cd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_807918e6e54fe207db68a74b2ce46fa6 |
| publicationDate |
2022-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2926535-T3 |
| titleOfInvention |
Improved method for high-level CRM production |
| abstract |
The present invention provides an improved method for the production of CRM197 in high yield using a genetically engineered Corynebacterium diphtheria strain having a higher copy number of the CRM197 gene, wherein the method comprises culturing the strain in a free medium. animal-derived components with one or more amino acids. (Automatic translation with Google Translate, without legal value) |
| priorityDate |
2017-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |