abstract |
The present invention provides, among other things, methods of treating or ameliorating an effect of a solid tumor present in a human. These methods include the intratumoral administration to humans of a unit dose of C. novyi, preferably C. novyi NT, colony-forming units (CFU), containing approximately 1 x 10 3 -1 x 10 7 CFU suspended in a carrier or acceptable solution. Methods for shrinking a solid tumor present in a human, methods for removing a solid tumor present in a human, a method for microscopically precise excision of tumor cells in a human, methods for treating or enhancing an effect of a solid tumor that has metastasized to one or more sites in a human, unit doses of C. novyi, preferably C. novyi NT, CFU, and kits for treating or ameliorating an effect of a solid tumor present in a human are also provided. (Automatic translation with Google Translate, without legal value) |