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publicationDate 2022-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2908067-T3
titleOfInvention Methods to modulate protein galactosylation profiles of recombinant proteins using peracetyl galactose
abstract A method for producing a recombinant protein with a decreased level of galactosylation, said method comprising culturing a host cell expressing said protein in a cell culture medium comprising a peracetyl galactose, wherein the peracetyl galactose is α-2-F peracetyl galactose or β-2-F peracetyl galactose, and wherein the concentration of peracetyl galactose in the cell culture medium before seeding is 60 µM.
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