http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2905950-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_48931f61f65ee74fda8bcfb3feded8ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_658df3b9d24eb5224b37aaf605741db6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D281-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D267-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D267-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2016-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81fb2f415b140971a398fdb76f26b4db http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78fb6ad38127ab0010af7e8cdcebabf6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1843da73ac4c07b5c34aa44e17502e26 |
| publicationDate | 2022-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2905950-T3 |
| titleOfInvention | Hepatitis B core protein modulators |
| abstract | A compound represented by: **(See formula)** where Y is S(O) and where y is 2; RZ is selected from the group consisting of H, methyl, ethyl, propyl, phenyl, and benzyl; Rm' and Rm are each independently selected from the group consisting of H and C1-6 alkyl (optionally substituted by one, two or three substituents each independently selected from halogen and hydroxyl); R21 is selected for each occurrence from the group consisting of H, halogen, and C1-6 alkyl; q is 1, or 2; R22 is selected for each occurrence from the group consisting of X2-phenyl (optionally substituted by one, two or three substituents represented by R63), phenyl (optionally substituted by one, two or three substituents represented by R63), 5- 6-membered (substituted by one, two or three substituents represented by R63), 9-10-membered bicyclic heteroaryl (optionally substituted by one, two or three substituents represented by R63); R' is selected, independently for each occurrence, from H, methyl, ethyl, and propyl; R" is selected, independently for each occurrence, from H, methyl, ethyl, propyl, butyl, -C(O)-methyl, and -C(O)-ethyl, or R' and R" taken together with the nitrogen to which are linked can form a 4-7 membered heterocycle; each of the R4, R5, R6, R7, R8, R9 and R10 moieties is independently selected for each occurrence from the group consisting of hydrogen, C1-6 alkyl, C2-6 alkynyl, C2-6 alkenyl, halogen, hydroxyl, nitro, cyano, and NR'R"; R63 is independently selected at each occurrence from the group consisting of halogen, hydroxyl, nitro, cyano, carboxy, C1-6 alkyl, -C(O)-O-C1-6 alkyl, heterocycle (optionally substituted by halogen or NR'R'), -C(O)-NR'R", -C(=NH)-NR'R", heteroaryl, phenyl, benzyl, C2-6 alkenyl, C2-6 alkynyl , C1-6 alkoxy, carboxy, NR'R", -C(O)-C1-6 alkyl, -C(O)-C1-6 alkoxy, C3-6 cycloalkyl, -S(O)w-C1-alkyl- 6 (where w is 0, 1 or 2), -S(O)w-NR'R" (where w is 0, 1 or 2), -NR'-S(O)w-C1-6 alkyl (where w is 0, 1 or 2), X2-R69; R69 is selected from the group consisting of H, halogen, hydroxyl, nitro, cyano, C1-6 alkyl, -C(O)-OC1-6 alkyl, heterocycle (optionally substituted by halogen or NR'R'),), -C(O)-NR'R", -C(=NH)-NR'R", heteroaryl, phenyl, C2-6 alkenyl, C2-6 alkynyl, C1-6 alkoxy, carboxy, NR'R", -C(O)-C1-6 alkyl, -C(O)-C1-6 alkoxy, C3-6 cycloalkyl, - S(O)w-C1-6 alkyl (where w is 0, 1, or 2), -S(O)w-NR'R" (where w is 0, 1, or 2), and -NR'-S( O)w-C1-6 alkyl (where w is 0, 1 or 2), X2 is selected from S(O)w (where w is 0, 1 or 2), O, CH2 or NR'; wherein for each occurrence, C1-6 alkyl may be optionally substituted with one, two, three or more substituents selected from the group consisting of halogen, hydroxyl, nitro, cyano, carboxy, C2-6 alkenyl, C2-6 alkynyl , NR'R", -NR'-S(O)w-C1-6 alkyl (where w is 0, 1 or 2), and S(O)w-NR'R" (where w is 0, 1 or two); C1-6 alkoxy may be optionally substituted with one, two, three or more substituents selected from the group consisting of halogen, hydroxyl, nitro, cyano, carboxy, C1-6 alkyl, NR'R", -NR'-S(O )w-C1-6alkyl (where w is 0, 1 or 2), and S(O)w-NR'R" (where w is 0, 1 or 2); and their pharmaceutically acceptable salts. |
| priorityDate | 2015-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 488.