| abstract |
An antibody molecule for use in the treatment of systemic sclerosis, wherein the antibody molecule binds to and neutralizes human TGFβ1, TGFβ2, and TGFβ3, and wherein the antibody molecule comprises: (i) a heavy chain comprising a variable domain heavy chain (VH), wherein the VH domain comprises the amino acid sequence of SEQ ID NO: 2, and a human IgG4 constant region, and (ii) a light chain comprising a light chain variable domain (VL), wherein the VL domain comprises the amino acid sequence of SEQ ID NO: 7. |