http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2905582-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c1ee19e6efdf91c1bf88bde9e9845ef |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D243-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D243-08 |
| filingDate | 2018-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc17392ca7cb3999c32ec3af595cd211 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_961f8d0edce10e14d91af7eaddb1b190 |
| publicationDate | 2022-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2905582-T3 |
| titleOfInvention | Alkoxyamine derivatives for the treatment of pain and pain-related conditions |
| abstract | A compound of general formula (I): **(See formula)** in which: R1 is a branched or unbranched C1-6 alkyl radical or a C1-6 haloalkyl radical; R2 is a 6-membered aryl optionally substituted by a halogen atom, a branched or unbranched C1-6 alkyl radical, a branched or unbranched C1-6 alkoxy radical, a C1-6 haloalkoxy radical, a C1-6 haloalkyl radical or a 5- or 6-membered hydroxyl or heteroaryl radical having at least one heteroatom selected from N, O and S; n and m are independently 0 or 1; Z1 and Z2 are independently selected from a hydrogen atom; a branched or unbranched C1-6 alkyl radical; a halogen atom; a branched or unbranched C1-6 alkoxy radical; a C3-6 cycloalkyl radical; a C1-6 haloalkyl radical and a C1-6 haloalkoxy radical; -W-R3 is in meta or para position; W is -(CH2)p-; -C(O)- or a bond; p is 1 or 2; R3 represents one of the following moieties: **(See formula)** or **(See formula)** in which Y 1 and Y2 are independently -CH2- or -C(O)-; Y3 is -CHR7- or -C(O)-; Y4 is -CH- or -N-R6; R4 and R5 are independently a hydrogen atom, a branched or unbranched C1-6 alkyl radical or a -(CH2)q-NRR' radical in which q is 0 or 1 and R and R' are independently a hydrogen atom or a branched or unbranched C1-6 alkyl radical; one or two of A, B and D represent -N- and the others are -CH-; E represents -N- or -CH-; R6 is a hydrogen atom; a branched or unbranched C1-6 alkyl radical or a -C(O)-CH2-NR6aR6b radical in which R6a and R6b are independently a hydrogen atom or a branched or unbranched C1-6 alkyl radical; R7 is a hydrogen atom or alternatively, R6 and R7 may form a 5- or 6-membered heterocycloalkyl group; R8 is a hydrogen atom, a branched or unbranched C1-6 alkyl radical; a halogen atom; a branched or unbranched C1-6 alkoxy radical; a hydroxyl radical; a C1-6 haloalkyl radical or a -NR8aR8b radical in which R8a and R8b are independently a hydrogen atom or a branched or unbranched C1-6 alkyl radical; R9 is a branched or unbranched C1-6 alkyl radical or a branched or unbranched C1-6 alkoxy radical; or a pharmaceutically acceptable salt, stereoisomer or solvate thereof. |
| priorityDate | 2017-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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