http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2903034-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01583a03f42afed5ad8b10ca8d127cd1 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2835 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2828 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54366 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2016-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6dab70b436de84e3a2111a412d35661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66d7d6208ecba1b5903f16a8cb9fe79d |
publicationDate | 2022-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2903034-T3 |
titleOfInvention | Device for the detection of misfolded proteins and methods for its use |
abstract | A diagnostic device for the detection of at least one protein in a biological sample from a mammal, comprising: a) a sample-receiving material, wherein said sample-receiving material is capable of receiving a biological sample; b) a detection reagent, wherein said detection reagent is reactive with at least one protein present in said biological sample; c) a trap, wherein said trap is in contact with the receiving material of the sample and wherein said trap is capable of separating the detection reagent bound to said at least one protein in said biological sample from the detection reagent that is not bound to said at least one protein in said biological sample, whereby said detection reagent bound to said at least one protein in said biological sample can flow through said trap, and whereby said detection reagent that is not is bound to said at least one protein in said biological sample is captured by said trap; d) a capillary bed, wherein said capillary bed is in contact with said trap, and wherein said capillary bed is configured to contain said biological sample after said biological sample flows through said trap, wherein said sample receiving material, said trap, and said capillary bed are configured to be in contact in sequence, wherein said capillary bed presents detection reagent if said at least one protein is present in said biological sample, and wherein said reagent of detection binds to at least one protein selected from the group consisting of a misfolded protein, a protein aggregate, a supramolecular protein aggregate, a fragment of a misfolded protein, a fragment of a protein aggregate, a fragment of a protein aggregate supramolecular, mixtures thereof and fragments of said mixtures. |
priorityDate | 2015-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 295.